Aspergillus felis – One-health & Public Health Implications
Invasive aspergillosis is a global health concern because of high mortality rates and treatment costs.
The aetiological agents of aspergillosis are ubiquitous in the environment and the likelihood that infection will occur following inhalation or implantation of spores largely depends on host factors. As the number of immunosuppressed patients worldwide rises, invasive aspergillosis has emerged as a major problem in several groups of these patients. Those at greatest risk include persons with hematological malignancies, hematopoietic stem cell transplant recipients, solid organ transplant recipients, individuals receiving high-dose corticosteroid treatment and persons with neutrophil deficiencies or dysfunction. Emerging at-risk populations include persons with acquired immunodeficiency syndrome, patients receiving intensive care and patients with chronic obstructive pulmonary disease.